Metaplastic carcinoma of the breast: A diagnostic dilemma
نویسندگان
چکیده
منابع مشابه
Metaplastic Carcinoma of Breast
Metaplastic carcinoma of breast (MBC) is a rare type of invasive breast carcinoma. It poses diagnostic challenge due to its varied histology and diverse differentiation. These are heterogenous group of tumors in which part or whole of the carcinomatous component is transformed into a metaplastic mesenchymal component and runs an aggressive clinical course. We present two cases of metaplastic ca...
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BACKGROUND. Metaplastic carcinoma is a rare form of breast carcinoma that often R. James Brenner, M.D. is confused with other benign and malignant entities. The diagnosis can be difficult Roderick R. Turner, M.D. to establish on both a clinical and conventional histopathologic basis. One report Vicki Schiller, M.D. recently described clinical and mammographic features dissimilar to the authors’...
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Metaplastic breast carcinoma (MBC) is a rare subtype of breast cancer characterized by coexistence of carcinomatous and sarcomatous components. Snail is a nuclear transcription factor incriminated in the transition of epithelial to mesenchymal differentiation of breast cancer. Aberrant Snail expression results in lost expression of the cell adhesion molecule E-cadherin, an event associated with...
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Pleomorphic lobular carcinoma of the breast has been identified as a histological variant of infiltrating lobular carcinoma (ILC) with poor prognosis. Thus, cytological recognition of this tumour is important. It is characterized by pleomorphism to a degree that contrasts with the cytologic uniformity of classic ILC. Due to this feature it is often misinterpreted as infiltrating ductal carcinom...
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ژورنال
عنوان ژورنال: Saudi Journal of Medicine and Medical Sciences
سال: 2015
ISSN: 1658-631X
DOI: 10.4103/1658-631x.149697